Perspectives For Future Innovation in Tendon repair (P4 FIT) fosters to build a new generation of ESRs with adequate skills to explore non-conventional therapeutic and diagnostic solutions by exploiting the technological advances in nanomedicine. The translation of innovative nanodevices carried out on integrated pre-clinical and vet/human clinical settings are expected to produce solid evidence-based datasets able to reduce fragmentation still limiting the impact of biomedical discoveries and to offer a unique opportunity for identifying new predictive biomarkers through the use of AI and deep learning data analysis. Working across disciplines and sectors, P4 FIT will foster the 15 ESRs to be creative, critical, autonomous intellectual risk takers at the frontiers of research with the R&I mind-set necessary for thriving careers. P4 FIT will allow to fill the EU gap in tendon healthcare, building up a generation of researchers able to develop nano-based biomedical devices by integrating biology advances to technology innovation, and to computational revolution. The P4 FIT cross-disciplinary approach includes 6 beneficiaries and 21 partner organizations (10 academic and 11 non-academic) from across Europe.