Indice degli argomenti
Informazioni generali sul corso
The course provides comprehensive and updated information about the molecular interactions that gametes put in place with the natural (the features male and female genitals) and artificial (culture media, media for cryopreservation of cells and tissues, storage systems) environment, with particular regard to the influence on them of the temperature.
This knowledge will enable the student to address critically the different methodologies applied to the cultivation, handling and cryopreservation of both human and animal gametes.
The course mainly aims to:
- Provide an updated scenario of the functional molecular interactions that can be impaired during cryopreservation (also altering epigenetics). The course will focus also on the protein/protein and protein/lipid interactions that can give a functional modulation of gametes.
- Describe the gametes biology at physiological and low temperatures.
- Describe the applications of gametes cryoconservation techniques.
- To introduce the fundamentals of computational modeling in cryobiology.
5 - 9 June 2017
12 - 16 June 2017
19 - 23 June 2017
Associate Professor (SSD VET / 02), Veterinary Physiology
Faculty of Veterinary Medicine
University of Teramo.
2004: PhD in "Endocrinology of Domestic Animals", University of Bologna
2002: First level University Master in "Reproductive Biotechnology", University of Teramo
1999: Degree in Veterinary Medicine, 110 cum laude, University of Pisa
The research of Dr. Bernabo is focused on Reproductive Biology of Mammals. In particular it id focused on:
- The adoption of computational models based on network theory (biological networks) to study the complex biological events, in particular in the acquisition of the fertilizing ability and the sperm-oocyte interaction.
- Study of the effect of exposure to electromagnetic fields on reproductive function;
- Study of the molecular mechanisms that control mammalian sperm capacitation.
Altogether were made more than 70 research products including articles in international scientific journals, participation in conferences and book chapters, of which 48 are indexed to Scopus (http://www.scopus.com/authid/detail.uri ? AuthorID = 55907939900), with an H index = 13.
Unit I - Physiology of gametes at low temperature
Unit II - Cryopreservation of gametes
Unit III - Introduction to computational modeling in cryobiology